I am having very good luck with a Necro/Archer..
100 Spririt Speak
100 Anatomy(trying to find a 120)
110 Tactics(trying to find a 120)
Here is the basic premise. This is a PVM template. Necro is there for Vampiric Embrace and the Hit Point Leach plus for certain things casting corpse skin works great. Chiv is there for Enemy of One and consecrate weapon/Divine Fury. Spirit Speak is going to be used for main healing, but I cannot let go of my Healing security blanket yet.. Eventually Healing will be replaced with 120's and topping off Chiv to 120...
I stand toe to toe with Miasma right now without having to flee.. Basically the same premise as a Sampire.. Do as much damage as possible to regen hit points, while not getting hit with 45DCI and hitting as much as possible with 45HCI.. Cast Divine Fury to increase SSI, along with as much SSI from bracelet,ring, and weapon.. Same goes for Damage Increase which I try and keep over 100...
When hitting Miasma with all buff in place(and I haven't even started down the Chugging Potions route yet for even more extras) I can hit for about 140 on the high end and 115 on the low..I am going to be re-doing all my bows to include BALANCE on all of them to aid in potion intake. I can take down Miasma in less than 45 seconds.. Not as impressive as a full out sampire, but having the standoff ability of an archer is great for doing things like Greater Dragons. I cannot stand toe to toe with a GD yet, the fire breath/physical hit combo is just to much for me to regen back in damage. .. One miss and I am dead.. I assume this would be the case for several of the hardest hitting monsters it the game... But then again, I am an archer and with a fast mount I can take down a Greater Dragon with this template in about 1 minute while doing my archer dance
My hope is to make this template the same as a Sampire.. I think with 120's in the right place it is doable...