My current favorite sampire template has healing instead of parry, so it doesn't matter if I use a one handed or two handed weapon. Since I chose fencing, I get the critical special move "feint" with a one handed weapon, the leafblade. This leaves me with a hand free to use potions in the rare case that my leeching, healing and confidence doesn't keep me high in hit points.
Then if you throw math at the issue, against an opponent who has 100 wrestling (Dread Horn only has 90!), parry only blocks a total of 8-12% of the total blows (depending on if hit lower attack is active), so you're only hit an average of once in every 12.5 seconds extra. (according to the stratics combat calculator
That is significant to some, but not to others. And since my tactic is to be useful in groups as well as alone, having healing instead of parry lets me heal the person standing next to me and still be a tank.
Parry is still a great skill to have, and the template in the original guide is still able to kill nearly everything in game (maybe not the Stygian Dragon, Lady Mel or the Slasher of Veils), but for my purposes, the healing-instead-of-parry version works best.