You should be able to, as drives are either PATA or SATA...you would need to find out which you have. Also, you should have a system restore disk that came with your PC, you will need this to reinstall Windows, as your motherboard will be proprietary (which can cause problems) and thus you may have problems installing Windows from a regular install disk. Also, that disk will have all of the drivers necessary for the peripherals on your PC. If you are not computer fluent, it may be best to take it in to a local shop and let them do the repair for you.